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 > IBBME > Faculty > Core Professors > C.A. Simmons
  • J. Andrysek
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  • A.C. Easty
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  • P.M. Gilbert
  • M.D. Grynpas
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  • O. Levi
  • K. Masani
  • A. McGuigan
  • A. Mihailidis
  • M.K. Nagai
  • M.R. Popovic
  • M. Radisic
  • J. Rocheleau
  • J.P. Santerre
  • M.V. Sefton
  • M.S. Shoichet
  • C.A. Simmons
  • E.D. Sone
  • D.A. Steinman
  • P. Trbovich
  • K. Truong
  • A. Wheeler
  • W. Wong
  • C.M. Yip
  • P. Yoo
  • L. You
  • P. Zandstra
  • J. Zariffa

C.A. Simmons

photo 

Associate Professor

  • Institute of Biomaterials & Biomedical Engineering
  • Department of Mechanical & Industrial Engineering
  • Faculty of Dentistry
  • Canada Research Chair in Mechanobiology

Contact Information

Email:  c.simmons@utoronto.ca
Website: http://cml.mie.utoronto.ca/doku.php

5 King's College Road, Room 221
Toronto, ON
Canada  M5S 3G8
Tel:  416-946-0548
Fax:  416-978-7753

Research Interests

Cellular mechanobiology, biomechanics, tissue engineering, and biomedical engineering. Approaches integrate experimental and computational cell mechanics with state-of-the-art quantitative cellular and molecular biology. Current applications include stem cell-based tissue engineering; mechanobiological studies of heart valve calcification; and the development of novel technologies for high throughput mechanobiology.

Positions available for graduate and undergraduate students

Recent Publications

Osteocyte apoptosis regulates osteoclast precursor adhesion via osteocytic IL-6 secretion and endothelial ICAM-1 expression. Cheung WY, Simmons CA, You L. Bone. 2012 Jan. 50(1):104-10.

Hydrogel Substrate Stiffness and Topography Interact to Induce Contact Guidance in Cardiac Fibroblasts. Al-Haque S, Miklas JW, Feric N, Chiu LL, Chen WL, Simmons CA, Radisic M. Macromol Biosci. 2012 Oct. 12(10):1342-53. 2012 Aug 27.

The elastic properties of valve interstitial cells undergoing pathological differentiation.
Wyss K, Yip CY, Mirzaei Z, Jin X, Chen JH, Simmons CA. J Biomech. 2012 Mar 15. 45(5):882-7.

A digital microfluidic platform for primary cell culture and analysis. Srigunapalan S, Eydelnant IA, Simmons CA, Wheeler AR. Lab Chip. 2012 Jan 21. 12(2):369-75. 

An improved texture correlation algorithm to measure substrate-cytoskeletal network strain transfer under large compressive strain. Zhao R, Simmons CA. J Biomech. 2012 Jan 3. 45(1):76-82. Epub 2011 Oct 24.

Calcific aortic valve disease: not simply a degenerative process: A review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update. Rajamannan NM, Evans FJ, Aikawa E, Grande-Allen KJ, Demer LL, Heistad DD, Simmons CA, Masters KS, Mathieu P, O'Brien KD, Schoen FJ, Towler DA, Yoganathan AP, Otto CM. Circulation. 2011 Oct 18. 124(16):1783-91.


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