Biomedical engineering is an interdisciplinary field that seeks to integrate the principles of medicine and biology with those of engineering. It applies the methods of engineering, the physical sciences and mathematics to the solution of problems in the clinical and life sciences, and uses the principles and techniques of the life sciences in engineering. The Institute of Biomaterials and Biomedical Engineering (IBBME) is an interdisciplinary organization based in the Faculties of Applied Science and Engineering, Dentistry, and Medicine. It was created in January 1999 as a merger of the Institute of Biomedical Engineering, the Centre for Biomaterials, and the tissue engineering research group principally in the Department of Chemical Engineering and Applied Chemistry. The core and cross-appointed faculty members have strong backgrounds in biomedical engineering and one or more of the core disciplines that form the basis of this interdisciplinary field; some are primarily engineers, while others are life scientists or physicians.