Professor, Canada Research Chair in Nanobioengineering & Director
BSc (U of Illinois-Urbana Champaign), PhD (Indiana University), FAIMBE
Research Stream: Molecular Engineering
Laboratory Website: http://inbs.med.utoronto.ca/
Email: email@example.com | Tel: 416-946-0020 | Office: RS407
Additional Contact Information
Rosebrugh Building (RS), 164 College Street, Room 407, Toronto, Ontario M5S 3G9 Canada
- Institute of Biomaterials & Biomedical Engineering
- Department of Chemical Engineering & Applied Chemistry
- Department of Chemistry
- Department of Materials Science & Engineering
- Donnelly Centre for Cellular & Biomolecular Research
Professor Warren Chan’s Integrated Nanotechnology & Biomedical Sciences Laboratory is interested in studying and understanding the proteomic and genomic changes associated with abnormal cells (e.g., cancer cells or virally-infected cells) and tissues. We aim to elucidate the cell’s molecular dynamics by using recent developments in nanotechnology (e.g., inorganic nanostructures), microtechnology (e.g., micro-electromechanical systems and capillary flow systems), and molecular engineering (e.g., phage-display) as well as engineering new instrumentation and techniques to address biological questions. A fundamental understanding of molecular processes with technology developments should lead to the design of novel diagnostic schemes and therapeutic strategies.
Stories & Media
Researchers in Dr. Warren Chan's lab have been developing three-dimensional (3D) imaging tools to map out cellular and sub-cellular components of organs in the body. Understanding the components in and around a tumour will allow for a more effective drug delivery, improving chemotherapy. As a result, the accuracy will lessen the chance of the drugs effecting healthy tissue and causing unintended side effects in the patient.
- Human Umbilical Vein Endothelial Cells (nuclei stained in blue) are grown within a microfluidic channel and subjected to flow shear in order to align their actin fibres (green) in the direction of flow. VE-Cadherin protein expression (red) shows the cell membranes are cross-linked to each other, allowing all of the individual cells to resist being washed away.
The current director of IBBME, Dr. Warren Chan, shares his thoughts on the evolving role of the biomedical engineering field and how it will shape healthcare.
"A biomedical engineer believes in the idea of convergence, where concepts from different fields are merged to solve an important scientific problem."
- How do you bring complex multi-step assays to resource- scarce areas? These multi-coloured, water-soluble pills each represent multiple steps in an assay, allowing scientists to carry out high precision experiments in resource-scarce areas.