MD (Toronto), FRCSC
Research Stream: Biomaterials, Tissue Engineering & Regenerative Medicine
+1 416 864-6003 (office)
- Division of Orthopaedic Surgery, Department of Surgery
- Orthopaedic Surgeon & Head, Division of Orthopaedic Surgery & Scientist, Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St. Michael’s Hospital
- Institute of Biomaterials & Biomedical Engineering
- Institute of Medical Science
Biomechanics, gene and cell based therapies, clinical trials, polytrauma, fracture healing, implant design, arthroplasty
My research has focused upon the care of patients with musculoskeletal injuries. My basic research interests include the systemic response to trauma, gene therapy, biomechanics, bone substitutes, and the stimulation of fracture healing. My clinical research interests include computer assisted surgery, clinical trials and outcomes studies. I have received international recognition for my research efforts including the Edouard J. Samson Award for a Canadian orthopaedic surgeon with the greatest impact on research in the last five years, the Founder’s Medal for Research (Canadian Orthopaedic Research Society) three times, the Bovill Award for best paper from the Orthopedic Trauma Association twice, the Neer Award from the American Shoulder and Elbow Surgeons, the Best Poster Award from the Orthopaedic Trauma Association twice, the Best Paper Award from the International Society for Fracture Repair, the CORE/ACORE Award from the Canadian Orthopaedic Association, the George Armstrong Peters Award from the University of Toronto, the North American traveling fellowship and the ABC traveling fellowship.
The mission of the Martin Orthopaedic Biomechanics Lab is to measure and improve the biomechanical performance of human and artificial bone, joint replacements and fracture fixation implants, and new biomaterials that can enhance patient quality of life, advance surgical techniques, and reduce health care system costs.
The overall goal of the musculoskeletal research laboratory at St. Michael’s Hospital is dedicated to developing novel biological therapies for non-healing musculoskeletal injuries in bone and soft-tissue, with the ultimate aim being translation to clinical trials in human patients. Current research is focused on the use of stem cell therapies to improve healing in complex fractures and rotator cuff injuries using animal based models.
Aziz MS, Tsuji MR, Nicayenzi B, Crookshank MC, Bougherara H, Schemitsch EH, Zdero R:Biomechanical measurements of stopping and stripping torques during screw insertion in five types of human and artificial humeri. Proc Inst Mech Eng H: 2014: 228(5): pp 446-455.
Crookshank MC, Beek M, Hardisty MR, Schemitsch EH, Whyne CM: 3D atlas-based registration can calculate malalignment of femoral shaft fractures in six degrees of freedom. Comput Aided Surg: 2014: 19(1-3): pp 48-56.
Li R, Nauth A, Gandhi R, Syed K, Schemitsch EH: BMP-2 mRNA expression after endothelial progenitor cell therapy for fracture healing. J Orthop Trauma: 2014: 28 (S1): pp S24-7.
Bagheri ZS, Tavakkoli Avval P, Bougherara H, Aziz MS, Schemitsch EH, Zdero R: Biomechanics of a new CF/Flax/Epoxy Plate versus a traditional metal plate for Vancouver B1 femur fractures: An experimental and computational study. J Biomech Eng: 2014: May Epub.
Zdero R, Bagheri ZS, Rezaey M, Schemitsch EH, Bougherara H: The biomechanical effect of loading speed on metal-on-UHMWPE contact mechanics. Open Biomed Eng J: 2014: 16;8: pp 28-34.
Sanders DW, Bhandari M, Guyatt G, Heels-Ansdell D, Schemitsch EH, Swiontkowski M. Tornetta P 3rd, Walter S: The critical sized defect in the tibia: Is it critical? Results from the SPRINT Trial. J Orthop Trauma: 2014: Epub.